{"id":3640,"date":"2024-05-20T18:00:00","date_gmt":"2024-05-20T21:00:00","guid":{"rendered":"https:\/\/nave.vet.br\/?p=3640"},"modified":"2024-05-20T18:02:37","modified_gmt":"2024-05-20T21:02:37","slug":"cetamina-na-mpa","status":"publish","type":"post","link":"https:\/\/nave.vet.br\/en\/video-aulas\/nave-tretas\/cetamina-na-mpa\/","title":{"rendered":"Have you used ketamine as premedication in Dogs and Cats? Really? - NAVE Discussion #3"},"content":{"rendered":"<div id=\"advads-3985934353\" class=\"advads-antes-do-post advads-entity-placement\" style=\"margin-bottom: 30px;margin-left: auto;margin-right: auto;text-align: center;\"><div class=\"advads-antes-do-post advads-entity-placement\" style=\"text-align: center;\" id=\"advads-1366537371\"><div id=\"advads-1487759271\"><a href=\"https:\/\/vetnar.com.br\/pos\/\" aria-label=\"Banner Vetnar &#8211; pos\"><img src=\"https:\/\/i0.wp.com\/nave.vet.br\/wp-content\/uploads\/2025\/03\/Banner-Vetnar-pos.gif?fit=1000%2C137&#038;ssl=1\" alt=\"\"  width=\"1000\" height=\"137\"   \/><\/a><\/div><\/div><\/div>\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe title=\"Voc\u00ea USA CETAMINA na MPA de C\u00e3es e Gatos\u2753 S\u00e9rio\u2753 - NAVE Tretas #3\" width=\"800\" height=\"450\" src=\"https:\/\/www.youtube.com\/embed\/0WBYF8mHYGg?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<p>In this video, we will discuss a bit about the use of ketamine as a sedative in preanesthetic medication for dogs and cats. This practice has been common among vets, but do we really achieve sedation with ketamine?<\/p>\n\n\n\n<p>If we consider the main effect of preanesthetic medication, which is sedation, ketamine won't help us. It actually promotes cerebral depression, mainly in the cortex, reducing sensations of touch, pain, vision, and temperature. However, other areas are stimulated, especially the limbic system, which is related to emotions. So, with the use of ketamine, we have stimulation of some parts of the brain and inhibition of others. Additionally, it does not promote muscle relaxation; on the contrary.<\/p>\n\n\n\n<p class=\"translation-block\">It's true that those who use ketamine in preanesthetic medication administer much lower doses than those that would cause dissociative anesthesia. However, there are few studies that have evaluated the efficacy of ketamine in \"subanesthetic\" doses as a sedative. In a <a href=\"https:\/\/doi.org\/10.1016\/j.vaa.2020.11.010\" target=\"_blank\" rel=\"noreferrer noopener\">study in dogs<\/a> , where they received 3 mcg\/kg of dexmedetomidine + 0.3 mg\/kg of methadone and 1 or 2 mg\/kg of ketamine, the authors found that sedation worsened in animals that received ketamine, with some animals showing drooling and dysphoria, clearly demonstrating the psychomimetic effects of this medication.<\/p><div id=\"advads-1746501758\" class=\"advads-adsense-in-article advads-entity-placement\"><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-9687921986569993\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display:block; text-align:center;\" data-ad-client=\"ca-pub-9687921986569993\" \ndata-ad-slot=\"1211285291\" \ndata-ad-layout=\"in-article\"\ndata-ad-format=\"fluid\"><\/ins>\n<script> \n(adsbygoogle = window.adsbygoogle || []).push({}); \n<\/script>\n<\/div>\n\n\n\n<p>On the other hand, in a recent study with cats (Pinho, 2024) who received 7 mcg\/kg of dexmedetomidine + 0.3 mg\/kg of methadone + 1 mg\/kg of ketamine, the addition of ketamine was beneficial, promoting intense sedation in the animals, with none of them showing psychomimetic effects. An important factor is that they used docile, easily handled cats. This certainly could have influenced the results.<\/p>\n\n\n\n<p>That's a good point. In feral cats, it's often challenging to handle them without ketamine. However, when using higher doses, it's no longer preanesthetic medication but rather chemical restraint or almost dissociative anesthesia.<\/p>\n\n\n\n<p>I believe that if we use the medications commonly used in premedication, such as phenothiazines, alpha 2 agonists, and opioids, especially combined, we can achieve adequate sedation in dogs and cats without the need to dissociate the animal. However, it's worth remembering that we need to maintain a quiet environment and give time for the drugs to take effect.<\/p>\n\n\n\n<p>But I agree that this approach is widely carried out nowadays... and it will depend on how the professional sees it. I'm just discussing here the effect of ketamine as a sedative... what it doesn't promote...<\/p>\n\n\n\n<hr class=\"wp-block-separator aligncenter has-alpha-channel-opacity\"\/>\n\n\n\n<h6 class=\"wp-block-heading\" id=\"leia-tambem\">Read also about:<\/h6>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.youtube.com\/playlist?list=PLjCHeRFiW1DhPRMwwRPw3vVvN0vaQpOwh\" target=\"_blank\" rel=\"noopener\"><\/a><a href=\"https:\/\/nave.vet.br\/en\/video-aulas\/anestesia-inalatoria\/\"><\/a><a href=\"https:\/\/nave.vet.br\/en\/video-aulas\/anestesia-dissociativa-anestesia-e-o-basico-11\/\">Dissociative Anesthesia - Anesthesia Unravelled #11<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.youtube.com\/playlist?list=PLjCHeRFiW1DiDtWyC448p56aam9vcG0yg\" target=\"_blank\" rel=\"noopener\"><\/a><a href=\"https:\/\/nave.vet.br\/en\/video-aulas\/circuitos-anestesicos\/\"><\/a><a href=\"https:\/\/nave.vet.br\/en\/video-aulas\/nave-responde\/anestesicos-dissociativos\/\">Dissociative Anesthetics - NAVE Answer!<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/nave.vet.br\/en\/posts\/2022-aaha_pain_management_guidelines\/\"><\/a><a href=\"https:\/\/nave.vet.br\/en\/video-aulas\/nave-responde\/vaporizador-universal\/\"><\/a><a href=\"https:\/\/nave.vet.br\/en\/posts\/cetamina-como-adjuvante-analgesico\/\">Beyond dissociative anesthesia: Ketamine as an analgesic adjuvant.<\/a><\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator aligncenter has-alpha-channel-opacity\"\/>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p><em>Find out more:<\/em><br><a href=\"https:\/\/doi.org\/10.1016\/j.vaa.2020.11.010\" target=\"_blank\" rel=\"noreferrer noopener\">&#8211; Arenillas et al. Sedative and analgesic effects of two subanaesthetic doses of ketamine in combination with methadone and a low dose of dexmedetomidine in healthy dogs. Vet Anaesth Analg, 48:545-553,2021.<\/a><br>&#8211; Pinho ISR. Influ\u00eancia de uma dose subanest\u00e9sica de cetamina sobre o grau de seda\u00e7\u00e3o, vari\u00e1veis fisiol\u00f3gicas e dose de propofol em gatos premedicados com dexmedetomidina e metadona: estudo cl\u00ednico, prospectivo e randomizado. UFRGS. PPG em Ci\u00eancias Veterin\u00e1rias. Disserta\u00e7\u00e3o. 2024, 31p.<\/p>\n\n\n\n<hr class=\"wp-block-separator aligncenter has-alpha-channel-opacity\"\/>\n\n\n\n<p><strong>Suggestions? Thoughts? Comments? Share!<\/strong><\/p>","protected":false},"excerpt":{"rendered":"<p>Have you use ketamine as a sedative in preanesthetic medication for dogs and cats? Then check out this post to find out why I am extremely reluctant to use ketamine as a sedative in dogs and cats...<\/p>","protected":false},"author":2,"featured_media":3644,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"video","meta":{"give_campaign_id":0,"colormag_page_layout":"default_layout","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1228,3,2],"tags":[355,1076,1073,633,14,29,1069,343,352,1070,1072,1244,1075,361,1074,351,344,357,1246,353,1245,364,781,1071],"class_list":["post-3640","post","type-post","status-publish","format-video","has-post-thumbnail","hentry","category-nave-tretas","category-posts","category-video-aulas","tag-anestesia-dissociativa","tag-anestesia-dissociativa-veterinaria","tag-anestesia-em-cachorro","tag-anestesia-em-caes","tag-anestesia-veterinaria","tag-anestesia-veterinaria-2","tag-anestesicos-dissociativos","tag-cetamina","tag-cetamina-anestesia","tag-cetamina-efeitos","tag-cetamina-s","tag-cetamina-sedativo","tag-cetamina-veterinaria","tag-como-usar-ketamina","tag-dissociativa-veterinaria","tag-dissociative-anesthesia","tag-dissociatives","tag-efeitos-ketamina","tag-kcetamina-como-sedativo","tag-ketamina","tag-ketamina-sedacao","tag-nave-anestesia","tag-naveabc","tag-quetamina","post_format-post-format-video"],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/nave.vet.br\/wp-content\/uploads\/2024\/05\/thumbanil-cetamina-mpa.webp?fit=1280%2C720&ssl=1","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/nave.vet.br\/en\/wp-json\/wp\/v2\/posts\/3640","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nave.vet.br\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nave.vet.br\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nave.vet.br\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nave.vet.br\/en\/wp-json\/wp\/v2\/comments?post=3640"}],"version-history":[{"count":8,"href":"https:\/\/nave.vet.br\/en\/wp-json\/wp\/v2\/posts\/3640\/revisions"}],"predecessor-version":[{"id":3656,"href":"https:\/\/nave.vet.br\/en\/wp-json\/wp\/v2\/posts\/3640\/revisions\/3656"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nave.vet.br\/en\/wp-json\/wp\/v2\/media\/3644"}],"wp:attachment":[{"href":"https:\/\/nave.vet.br\/en\/wp-json\/wp\/v2\/media?parent=3640"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nave.vet.br\/en\/wp-json\/wp\/v2\/categories?post=3640"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nave.vet.br\/en\/wp-json\/wp\/v2\/tags?post=3640"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}